Antiepileptic Drugs to Treat Psychiatric Disorders by Susan L. McElroy, Paul E. Keck Jr., Robert M. Post

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By Susan L. McElroy, Paul E. Keck Jr., Robert M. Post

Several antiepileptic medications (AEDs) now have regulatory symptoms for treating bipolar ailment. there's growing to be facts that AEDs more often than not have a number of worthy psychotropic results. Antiepileptic medicinal drugs to regard Psychiatric problems is the 1st accomplished, clinically orientated reference at the use of AEDs to regard various psychiatric stipulations resembling temper, psychotic, anxiousness, substance use, consuming, and character problems. Written through the best scientific specialists, the booklet is prepared by means of psychiatric ailment for simpler info collecting, permitting physicians to exploit the textual content as a standalone reference.

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34. Ramsay RE, Rowan AJ, Slater JD, et al. The VA cooperative study group. Effect of age on epilepsy and its treatment: results from the VA cooperative study. Epilepsia 1994; 35 (suppl 8):91 (abstr). 35. Brodie MJ, Overstall PW, Giorgi L. for the UK Lamotrigine Elderly Study Group. Multicentre, double-blind, randomised comaprison between lamotrigine and carbamazepine in elderly patients with newly diagnosed epilepsy. Epilepsy Res 1999; 37:81–87. 36. Rowan AJ, Ramsay RE, Collins JF, et al. VA cooperative study 428 group.

The likelihood of further seizures, however, is considerably higher after two seizures. Long-term prophylactic use of AEDs is also not indicated after provoked seizures, but there are situations where treatment might be started after a first attack. , in a fragile elderly patient with seizure onset after a stroke. On the other hand, some patients with very short and mild seizures with long intervals might prefer to stay off treatment. The present strategy is based on the assumption that treatment with AEDs is purely symptomatic and does not affect the natural course of epilepsy.

57. Johannessen SI, Tomson T. Pharmacokinetic variability of newer antiepileptic drugs: when is monitoring needed? Clin Pharmacokin 2006; 45:1061–1075. 58. Annegers JF, Hauser WA, Elveback LR. Remission of seizures and relapse in patients with epilepsy. Epilepsia 1979; 20(6):729–737. 59. Specchio LM, Beghi E. Should antiepileptic drugs be withdrawn in seizure-free patients? CNS Drugs 2004; 18(4):201–212. 60. Medical Research Council Antiepileptic Drug Withdrawal Study Group. Randomized study of antiepileptic drug withdrawal in patients in remission.

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